Figure 1 below shows data from one of the first experiments demonstrating LTP by Bliss and Lomo (1973; we looked at this in class). The y-axis represents measurements of fEPSP peak amplitude as a percent of baseline. The arrows indicate points at which high frequency stimuli were given.
Figure 2 below depicts an example of a field EPSP prior to high frequency stimulation. The vertical line is the stimulus artifact (this is the fEPSP measurement WHILE the stimulation was happening – you can ignore it).
What would the fEPSP look like at 1 hour and 4 hours? Please draw and label them on Figure 2 above and upload it here. You can draw by hand and snap a pic, or add the traces digitally and upload the file.
- Attachment 1
- Attachment 2