In gluconeogenesis, pyruvate carboxylase first converts pyruvate to oxaloacetate which is then converted to phosphoenolpyruvate (PEP) by PEP…

Hi there I need help with figuring out the two questions above thank you

1. In gluconeogenesis, pyruvate carboxylase first converts pyruvate to oxaloacetate which is thenconverted to phosphoenolpyruvate (PEP) by PEP carboxykinase:ATPADP + PiGTPGDPCO2CH2cooOOC-H22-03PO-cooHCO,(a) Calculate the biochemical standard-state free energy change (4Go’) for the overall reaction.Assume the AGo’ values for ATP and GTP hydrolysis are the same.[5](b) Calculate the free energy change in an erythrocyte whereby the concentrations of pyruvate,PEP, ATP, ADP and Pi are 50 UM, 25 UM, 2.0 mM, 0.15 mM and 1.0.mM, respectively.Assume [ATP] = [GTP] and [ADP] = [GDP].MacBook ProOODDDF3000F6F7DIIDDF9F10CA%A*67OO

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