The following reaction is catalyzed by phosphoglucomutase:

The following reaction is catalyzed by phosphoglucomutase:

Glucose 1-phosphate  Glucose 6-phosphate

The reaction started with 20mM glucose 1-phosphate and no glucose 6-phosphate, and the final equilibrium mixture at 25 °C and pH 7 contains 1.0 mM glucose 1-phosphate and 19 mM glucose 6- phosphate.

a. Calculate the equilibrium constant.

b. Calculate the free energy change.

c. Is the reaction spontaneous or non-spontaneous? Endergonic or exergonic?

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