The following reaction is catalyzed by phosphoglucomutase:
Glucose 1-phosphate Glucose 6-phosphate
The reaction started with 20mM glucose 1-phosphate and no glucose 6-phosphate, and the final equilibrium mixture at 25 °C and pH 7 contains 1.0 mM glucose 1-phosphate and 19 mM glucose 6- phosphate.
a. Calculate the equilibrium constant.
b. Calculate the free energy change.
c. Is the reaction spontaneous or non-spontaneous? Endergonic or exergonic?